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High Pressure Homogenizer

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Ultra-high pressure cell wall breaking homogenizer

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Ultra-high pressure cell wall breaking homogenizer

High pressure homogenizer can disperse particles into micron or even nanometer scale.

  • Item NO.:

    FB-110X39

  • Lead Time:

    7-15 day

  • Working pressure:

    0~2000bar/200mpa

  • Working flow:

    220V/380V or customize

  • Standard voltage:

    2.2kw

  • Standard power:

    ≥15ml

  • Minimum processing volume:

    ≤500um

  • Maximum feed particle size:

    ≤10000cPs

  • Maximum feed viscosity:

    ≤145℃

  • Maximum operating temperature:

    5~15L/H
  • Product Details

Ultra-high pressure cell wall breaking homogenizer is a high-pressure device specially used for cell wall breaking. It can break the cell wall through extremely high pressure to release the effective components in the cell. This equipment is widely used in biotechnology, pharmaceuticals, food processing and other fields, and is especially suitable for processing biological materials with hard cell walls, such as yeast, fungi, algae, etc. The following is a det

ailed introduction to the ultra-high pressure cell wall breaking homogenizer:


Design and functional features


  1. Ultra-high pressure system: The equipment can generate ultra-high pressures of thousands of bars or even more than 1000 MPa. Through this extremely high pressure, the material undergoes strong compression, shearing, impact and cavitation effects in the homogenization chamber, resulting in the rupture of the cell wall, thereby releasing substances inside the cell, such as proteins, lipids and nucleic acids.
  2. High cell wall breaking efficiency: The ultra-high pressure cell wall breaking homogenizer can quickly and effectively break the cell wall, and the wall breaking rate can usually reach more than 95%, which is suitable for applications that require efficient extraction of intracellular components.
  3. Gentle treatment: Since the material processing time during the homogenization process is very short and the equipment can be equipped with a cooling system, cell wall breaking can be achieved at a lower temperature, effectively avoiding the damage of heat-sensitive components by high temperature.
  4. Homogenizing valve design: The homogenizing valve is the core component of the equipment. It is usually made of wear-resistant materials and has extremely high processing precision to withstand ultra-high pressure environments. Through the design of the homogenizing valve, the material can be subjected to strong physical effects in a short time to complete the cell wall breaking process.
Working Principle
  • The working principle of the ultra-high pressure cell wall breaking homogenizer is based on high pressure homogenization technology. Its core mechanism is to use ultra-high pressure to pass the material through the narrow homogenization valve port, producing strong physical effects (such as shear, impact, cavitation, etc.), thereby achieving cell wall rupture.
  • Pressurization stage: The material is pressurized to ultra-high pressure (several thousand bars or even higher) by a high-pressure pump, and the material molecules are compressed under this pressure.
  • Homogenization process: In the homogenization valve, the material passes through the narrow homogenization channel in an instant, generating extremely strong shear force and impact force, and the cell walls in the material are broken.
  • Cavitation effect: In the process of the material passing through the homogenization valve, due to the sharp decrease in pressure, bubbles in the liquid are quickly formed and broken, further enhancing the wall breaking effect.


Design pressure
 1800bar/180MPa/26100psi
Working pressure
 1500bar/150MPa/21750psi
Working flow
 15~39L/H
Standard voltage
  220V/380V
Standard power
 2.2kw
Minimum processing volume
 100ml
Maximum feed particle size
 ≤500um
Maximum feed viscosity
 ≤10000cPs
Maximum operating temperature
  ≤99℃
Functional characteristics:
★ The pump body is split design, easy to disassemble and clean.
★ The whole machine is GMP designed and can be operated online for SIP/CIP.
★ It has ultra-high pressure design, and the pressure can reach 2000bar/29000psi.
★ Single-stage turbulent homogenizing valve design, optional alloy or diamond or ceramic valve components.
★ Online built-in jacket temperature control 4~10℃.
★ Digital pressure display, accurate to 1bar.
★ PLC touch screen control, data can be monitored, copied and stored.
★ Frequency conversion control device with soft start function.
★ The flow rate can be adjusted according to the output without consuming materials.
★ Online emptying, zero residue can be achieved inside.
★ The power end is equipped with a high-power motor to ensure stable operation under high pressure.
★ Special feed valve design, no exhaust, can be fed directly.
★ The material residue is zero, especially suitable for the research and development of pharmaceuticals with expensive raw and auxiliary materials.
★ The manufacturer has a mechanical manufacturing and processing license.
★The core parts of the whole machine have patent intellectual property protection.
★Passed ISO9001 quality management system certification.
★Passed EU CE mechanical safety certification.


  











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